Allogeneic Hematopoietic Stem Cell Transplantation for Patients With Light Renal Failure

Abstract

Although renal function may affect the outcome of allogeneic hematopoietic stem cell transplantation (HSCT), mildly reduced renal function which is defined as serum creatinine level between 1.2 to 2.0 mg/dl did not correlate with non-relapse mortality (NRM) in the analysis of hematopoietic cell transplantation comorbidity index (HCT-CI). Creatinine clearance rate (Ccr) is a useful and exact way to asses renal function. Impact of renal function which is evaluated using Ccr before HSCT on the outcome has not been investigated yet.