Abstract

The Centers for Disease Control and Prevention (CDC) had an annual budget of approximately $327 million to fund health departments and community-based organizations for core HIV testing and prevention programs domestically between 2001 and 2006. Annual HIV incidence has been relatively stable since the year 2000 [1] and was estimated at 48,600 cases in 2006 and 48,100 in 2009 [2]. Using estimates on HIV incidence, prevalence, prevention program costs and benefits, and current spending, we created an HIV resource allocation model that can generate a mathematically optimal allocation of the Division of HIV/AIDS Prevention’s extramural budget for HIV testing, and counseling and education programs. The model’s data inputs and methods were reviewed by subject matter experts internal and external to the CDC via an extensive validation process. The model projects the HIV epidemic for the United States under different allocation strategies under a fixed budget. Our objective is to support national HIV prevention planning efforts and inform the decision-making process for HIV resource allocation. Model results can be summarized into three main recommendations. First, more funds should be allocated to testing and these should further target men who have sex with men and injecting drug users. Second, counseling and education interventions ought to provide a greater focus on HIV positive persons who are aware of their status. And lastly, interventions should target those at high risk for transmitting or acquiring HIV, rather than lower-risk members of the general population. The main conclusions of the HIV resource allocation model have played a role in the introduction of new programs and provide valuable guidance to target resources and improve the impact of HIV prevention efforts in the United States.

Highlights

  • At the end of 2006, HIV prevalence among the adult and adolescent population in the United States was estimated at 1.1 million, with 21% unaware of their seropositivity [3]

  • The cumulative number of new HIV infections over five years predicted by the model is 192,000 under an optimized allocation of the $327 million budget, 223,000 in the baseline scenario which assumes the current allocation of the $327 million

  • Estimated size of the HIV- population, aged 13–64, in the US (2006) Estimated size of the high-risk population, aged 13–64, in the US Percentage of HIV positives unaware of their serostatus Estimated number of new HIV infections in the US (2006) Proportion of new infections that result from contact with an unaware positive

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Summary

Introduction

At the end of 2006, HIV prevalence among the adult and adolescent population in the United States was estimated at 1.1 million, with 21% unaware of their seropositivity [3]. A 2008 survey of 21 cities indicated that 19% of men who have sex with men (MSM) were HIV infected and 44% of those were unaware of their infection [4]. Annual HIV incidence has been relatively stable since the year 2000 [1] and was estimated at 48,600 cases in 2006 and 48,100 in 2009 [2]. Black and Hispanic populations in the US are disproportionately affected by HIV. In 2006, 44% and 18% of new HIV infections were among black individuals and Hispanics, respectively, while these populations represent 13% and 15% of the general US adult population, respectively [2]

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