Allergie alimentaire aux champignons de Paris cuits : à propos d’un cas rare

Abstract

Immediate food hypersensitivity to mushrooms is rare but potentially serious. We report the case of a 23-year-old atopic patient presenting an oral syndrome and high digestive symptoms (nausea, vomiting) when consuming cooked button mushrooms. He has no other history of food allergy. The cooked mushroom prick-test is strongly positive, with the appearance of a pseudopodic papule measured at 1.5cm from the main axis. The allergens in question are poorly characterized and may be modified by cooking, with the revelation of hidden epitopes after the conformational protein denaturation linked to heat. Cross-reactivity with Alternaria Alternata seems possible in view of the strong sensitization of our patient to the major allergens of this mold. Management is based on the eviction of all edible mushrooms, except in cases where tolerance to another species is proven. Wearing an emergency kit remains the rule. Its content should be adapted to the clinical characteristics of the reaction.