Abstract
Summary An outbreak of dermatitis in a joinery shop is reported. The condition affected four out of five persons sanding a Brazilian rosewood substitute, Machaerium scleroxylum Tul. The features and extent of the rash are described, with illustration of the most severely affected individual who also developed erythema multiforme-like lesions in some areas. Patch testing with the wood has confirmed it to be the cause. The importance of positive identification of the wood is stressed, particularly as the workers and suppliers of the wood were under the impression that it was genuine Brazilian rosewood (Dalbergia nigra All.). Further patch testing with a series of dalbergiones has confirmed previous observations that R-3,4-dimethoxydalbergione is the sensitizer. The reason for the associated cross-reactions with other dalbergiones is discussed. The strong sensitizing potential of R-3,4-dimethoxydalbergione is highlighted.
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