Abstract

Background: Allergic contact dermatitis (ACD) by anti-allergic agents is not so common. We have experienced 3 cases of Ketotifen induced ACD. Methods: We present 3 case studies visited in our Department of Ophthalmology of Tsurumi University between February 2012 and March 2013. Results: 3 patients were diagnosed ACD and treated with the other anti-allergic eye drops, 0.1% fluoromethorone eye drops and prednisolone ointment for blepharitis. Inflammations of theses lesions are healed within two weeks. Conclusions: ACD might be care even anti-allergic eye drops.

Highlights

  • Allergic contact dermatitis (ACD) is a form of contact dermatitis that is the manifestation of an allergic response caused by contact with a substance; the other type being irritant contact dermatitis (ICD) [1]

  • We present 3 cases of ocular allergic contact blepharitis induced by anti-allergic eye drops (Ketotifen fumarate)

  • Ketotifen is a second-generation noncompetitive H1-antihistamine and mast cell stabilizer. It is most commonly sold as a salt of fumaric acid, ketotifen fumarate, and is available in two forms of eye drop; vial or unit dose (UD)

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Summary

Introduction

Allergic contact dermatitis (ACD) is a form of contact dermatitis that is the manifestation of an allergic response caused by contact with a substance; the other type being irritant contact dermatitis (ICD) [1]. The most common cause of ACD of the lids and periorbital area is cosmetics applied to the hair, face, or fingernails rather than to the eye area itself. We present 3 cases of ocular allergic contact blepharitis induced by anti-allergic eye drops (Ketotifen fumarate).

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