Abstract
Case presentation: We present the case of a diabetic 73 year old male who worked as a farmer, with infiltrates in the right lower and middle lung lobes and with previous diagnosis of chronic obstructive bronchitis. Evaluation of our patient led to the diagnosis of allergic bronchopulmonary aspergillosis in the right lower and middle lobe. Fungal stains were positive for aspergillus. Based on the clinical, radiological and cytological findings, the patient was diagnosed with pulmonary aspergillosis and treated successfully with oral itraconazole and methylprednisolone. Systemic antifungal therapy plays an important role in preventing the morbidity and mortality. He was treated with oral methylprednisolone and itraconazole. Conclusion: Aspergillus infection after the inhalation of spores in the form of a hypersensitivity reaction and saprophytic colonization can be coexistent.
Highlights
Aspergillosis refers to the spectrum of disease caused by Aspergillus species acquired by inhalation of airborne spores
But some of them are very serious Pulmonary aspergillosis is classified as Invasive pulmonary aspergillosis (IPA), chronic necrotizing pulmonary aspergillosis (CNPA), Aspergilloma and Allergic bronchopulmonary aspergillosis (ABPA) [4]
Allergic bronchopulmonary aspergillosis (ABPA) is a complex hypersensitivity reaction in patients with asthma, which occurs when bronchi are colonized by the Aspergillus species and most commonly due to Aspergillus fumigatus
Summary
Aspergillosis refers to the spectrum of disease caused by Aspergillus species acquired by inhalation of airborne spores. This condition presents with a spectrum of illnesses, ranging from allergic reactions to colonization of pulmonary cavities to invasion and pyaemic spread to the brain, skin and other organs in the body [1,2,3] .There are different types of aspergillosis. Allergic bronchopulmonary aspergillosis (ABPA) causes inflammation in the lungs and allergy symptoms such as coughing and wheezing, but doesn’t cause an infection. Allergic bronchopulmonary aspergillosis (ABPA) is a complex hypersensitivity reaction in patients with asthma, which occurs when bronchi are colonized by the Aspergillus species and most commonly due to Aspergillus fumigatus. The incidence may be as high as 6% of patients with asthma [5].Repeated episodes of bronchial obstruction, inflammation and mucoid impaction can lead to bronchiectasis, fibrosis and respiratory compromise
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