Allergen-Specific IgE as a Biomarker of Exposure Plus Sensitization in Inner-City Adolescents With Asthma

Abstract

EC Matsui, HA Sampson, HT Bahnson; Inner-City Asthma Consortium. Allergy. 2010;65(11):1414–1422 These researchers sought to understand the relationship between allergen-specific immunoglobulin E (IgE) levels, exposure to indoor allergens, and asthma severity. There were 546 subjects, aged 12 to 20 years, with physician-diagnosed moderate-to-severe asthma enrolled at 10 centers around the United States as part of the Asthma Control Evaluation (ACE) study. Subjects underwent a 3-week run-in period in which asthma symptoms, medication use, pulmonary-function testing, and adherence data were collected. Skin …