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Abstract
Vaccination against viral and bacterial pathogens represents a challenging issue in allergic subjects, mainly concerning patients undergoing allergen immunotherapy (AIT). For this reason, an international survey has been performed involving a panel of experts who responded to a series of questions, also concerning the COVID-19 impact on allergen immunotherapy and vaccinations.The results showed that co-administration of vaccines and AIT requires caution, mainly during the pandemic era. Moreover, the choice of AIT product should be oriented considering also the safety profile.
Highlights
Vaccination against viral and bacterial pathogens represents a challenging issue in allergic subjects, mainly concerning patients undergoing allergen immunotherapy
Ulrich and colleagues analysed the data of 875 patients receiving subcutaneous immunotherapy (SCIT) and/or vaccination.[1]
A warning has been established for severe allergic reactions to both mRNA and non-mRNA COVID-19 vaccines.[2]
Summary
Vaccination against viral and bacterial pathogens represents a challenging issue in allergic subjects, mainly concerning patients undergoing allergen immunotherapy (AIT). Under the framework of the European Academy of Allergy and Clinical Immunology (EAACI), a group of experts conducted a web-based retrospective survey on practical and safety aspects of AIT during the COVID-19 era.[9] The outcomes showed that AIT starting was postponed in 60% of the participants, and maintenance AIT was continued by 75% (89% for sublingual immunotherapy, SLIT). An international survey explored the practical aspects of AIT and vaccination management during the COVID-19 pandemic. The large majority (95%) had an experience of about 200 patients being vaccinated for infectious diseases during AIT.
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