Abstract
Background: X-chromosome (ChrX) STR loci have been proven to be a useful tool for paternity testing, especially in some cases. In paternity testing, genetic markers on ChrX are only applicable when the disputed child is female. Methods: The author investigated allele frequency distribution of ChrX STR loci DXS6789 and HumSTRX1 in a sample of unrelated individuals (males and females) in Han population living in Chengdu, China, by using PCR and PAGE followed by silver staining. Results: Ten and six different alleles of DXS6789 and HumSTRX1 loci were detected, respectively. The genotype frequencies of DXS6789 and HumSTRX1 loci were in good agreement with the Hardy–Weinberg equilibrium. The observed heterozygosity of DXS6789 and HumSTRX1 loci were 0.795 and 0.748 in females, respectively. Conclusions: It is suggested that these ChrX markers are appropriate for the purposes of forensic analyses.
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