Abstract
All hail reproducibility in microbiome research
Highlights
At its core, microbiome research relies on complex and sophisticated statistical analyses of large datasets and their associated metadata
Microbiome research is, by its nature, a multi-disciplinary endeavor where experimentalists often work with biostatisticians, mathematicians, computer scientists, or epidemiologists
Data deposited into FigShare is permanently archived and redundantly backed up at major universities around the world through the CLOCKSS system, and a permanent digital object identifier (DOI) is supplied with each dataset
Summary
Microbiome research relies on complex and sophisticated statistical analyses of large datasets and their associated metadata (e.g., experimental parameters, sample characteristics). Reproducibility and extension are only possible if: data is and freely accessible and delivered in format that adheres to international standards; and analysis workflows and scripts are embedded in the publication. Microbiome research is transitioning from a descriptive and associative science to a translational science that will start impacting lives, we feel the time is right for the community to set standards for complete transparency and full reproducibility.
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