Abstract
The alkylation of imidazole-4(5)-carboxylic acid anilide and methyl ester with bromoacetic acid and its methyl ester in neutral and alkaline media yields, along with monoalkylation products, 1,3-bis(2-methoxycarbonylmethyl)-4-R-imidazolium bromide. The monoalkylation of methyl imidazole-4(5)-carboxylate yields a 1:1 mixture of the 1,4- and 1,5-isomers, and the monoalkylation of imidazole-4(5)-carboxylic anilide selectively provides the 1,4-isomer.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
