Abstract

3-Methyl-4-chloro-4,5,6,7-tetrahydrobenz[1,2-d]isoxazole was synthesized from 3-methyl-4-oxo-4,5,6,7-tetrahydrobenz[1,2-d]isoxazole. The compound is used in the alkylation of malonic ester and methoxytetralone enolates. Bi- and tetracyclic derivatives of the pyridine and hydropyridine series were obtained by catalytic hydrogenation of the alkylation products.

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