Abstract

This monograph is of great interest to physiologists, pharmacologists and physicians concerned with the medicolegal aspect of alcoholism. The author presents his own extensive studies of alcohol concentration in arterial, venous and capillary blood, in cerebrospinal fluid and in urine during the first two hours after taking various quantities of alcohol, on the fasting stomach and after food, and gives good critical summaries and evaluations of the relevant literature. The author's material includes also 400 medicolegal cases in which the amount of the alcohol ingested was unknown or in dispute. In the few cases tested the concentration of alcohol in the cerebrospinal fluid tended to exceed that in the arterial blood. The author studied also alcohol concentration in the blood of normal people not ingesting alcohol and accepts as probable the view that a trace of alcohol (production and ultimate oxidation) is part of normal metabolism and not dependent on

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