Abstract

From the leaves of Strychnos icaja Baill. a further seven alkaloids have been isolated and their structures determined: 16-hydroxystrychnine ( 1e), 21,22-α-epoxy-4-hydroxy-3-methoxy-N-methyl-sec.-pseudostrychnine ( 5c), 21,22-α-epoxy-4-hydroxy-N-methyl-sec.-pseudostrychnine 5a), 21,22-α-epoxy-2-methoxy-N-methyl-sec.-pseudostrychnine ( 5b), 21,22-α-epoxy-14-hydroxy-N-methyl-sec.-pseudostrychnine ( 6a), 21,22-α-epoxy-4,14-dihydroxy-N-methyl-sec.-pseudostrychnine ( 6b), and 14-hydroxy-N-methyl-sec.-pseudostrychnine ( 7). Jaminet's alkaloid B' is shown to be impure 21,22-α-epoxy-14-hydroxy-2,3-dimethoxy-N-methyl-sec.-pseudostrychnine ( 6c).

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