Abstract
Background: The simply prepared and characterized alkaline starch (AS) by a new co-grinding protocol represents a superior catalytic activity in two- or three-component synthesis of hydroquinazolinones from either 2-aminobenzonitrile, 2-aminobenzamide, or isatoic anhydride. All AS-catalyzed reactions occur in higher yield and faster than the earlier methodologies. These performances are due to the several basic sites and special polymeric structure of this green bioorganic base catalyst. Keywords: Alkaline starch, co-grinding, biopolymeric catalyst, organic base, hydroquinazolinones.
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