Abstract
This study evaluated the efficacy of cleanser solutions on denture biofilm removal by a crossover randomized clinical trial. Thirty two edentulous patients were instructed to brush their dentures (specific brush and liquid soap) three times a day (after breakfast, lunch and dinner) and to soak them (≥ 8 h) in: (C) control -water; (AP): alkaline peroxide; or (SH) 0.5% sodium hypochlorite. Each solution was used for 21 days (three cycles of 7 days). At the end of each cycle, the inner surfaces of maxillary dentures were disclosed (1% neutral red) and photographed (HX1 - Sony). Areas (total and stained biofilm) were measured (Image Tool software) and the percentage of biofilm calculated as the ratio between the area of the biofilm multiplied by 100 and total surface area of the internal base of the denture. Data were compared by means of generalized estimating equation (α=5%) and multiple comparisons (Bonferroni; α=1.67%). Immersion in SH reduced biofilm (%) (8.3 ± 13.3B) compared to C (18.2 ± 14.9A) and AP (18.2 ± 16.6A). The 0.5% sodium hypochlorite solution was the most efficacious for biofilm removal. Alkaline peroxides may not lead to further biofilm removal in patients with adequate denture maintenance habits.
Highlights
Complete denture hygiene is crucial for the maintenance of oral health for edentulous patients
Of the total of 39 patients, three were excluded, one for the impossibility to stay without the dentures during sleep and two for not using the products
This study provided data regarding the efficacy of two major chemical methods for overnight denture cleansing
Summary
Complete denture hygiene is crucial for the maintenance of oral health for edentulous patients. Hypochlorite solutions have been indicated as effective chemical method of hygienic [11,12,17,19,20]; the concentration is a factor that should be considered to prevent any adverse effects on the materials of the prosthetic devices [21,22]. The majority of these works evaluated the effectiveness of these solutions in short periods of immersion; few clinical studies have been carried out in compliance with approaches for minimizing biases [2]. Denture cleansers are still a reasonable subject for randomized controlled trials
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