Abstract

SummaryBackground:There is a relationship between physical activity and health-related quality of life (HRQL) in healthy people and in patients with ischemic heart disease (IHD). The purpose of this study was to determine whether this relationship between sports or recreational physical activity levels and HRQL has a dose-response gradient in patients with IHD.Methods:Using one generic and three IHD-specific HRQL questionnaires, differences in HRQL scores (adjusted for confounders) were determined for physically a) inactive vs. active patients and b) inactive vs. patients being active 1–2, 3–5, or >5 times per week.Results:Data were provided by 6143 IHD-patients (angina: N = 2033; myocardial infarction: N = 2266; ischemic heart failure: N = 1844). Regardless of diagnosis or instrument used, when patients were dichotomized as either inactive or active, the latter reported throughout higher physical and emotional HRQL (all p < 0.001; d = 0.25–0.70). When categorized by physical activity levels, there was a positive HRQL dose-response gradient by increasing levels of physical activity that was most marked between inactive patients and those being active 1–2 times per week (63 82%). Conclusions: Using generic and IHD-specific HRQL questionnaires, there seems to be an overall dose-dependent gradient betweenincreasing levels of sports or recreational physical activity and higher HRQL in patients with angina, myocardial infarction, and ischemic heart failure. The greatest bang for the public health buck still lies on putting all the effort in changing sedentary lifestyle to at least a moderate active one (1–2 times per week), in particular in cardiac rehabilitation settings.

Highlights

  • ObjectivesThe aim of this study was to examine if there would be a positive dose-response gradient between increasing levels of sports or recreational physical activity and higher health-related quality of life (HRQL) scores on different validated HRQL questionnaires in patients with angina, myocardial infarction (MI), or ischemic heart failure

  • Sociodemographic and clinical characteristics (Table 1) The cohort in this HeartQoL project substudy consisted of 6143 patients with ischemic heart disease (IHD)

  • 732 A little is better than none: the biggest gain of physical activity in patients with ischemic heart disease sults in this study provide substantiation of a positive health-related quality of life (HRQL) dose-response gradient in patients with IHD with increasing levels of physical activity levels associated with higher HRQL scores

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Summary

Objectives

The aim of this study was to examine if there would be a positive dose-response gradient between increasing levels of sports or recreational physical activity and higher HRQL scores on different validated HRQL questionnaires in patients with angina, MI, or ischemic heart failure

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