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Abstract
The continuing rapid progress towards a complete database of structural information on the human genome creates a challenge of ensuring that current schemes for classifying and naming receptors and ion channels effectively integrate this information with functional data to provide unambiguous principles for classification. In this article, Paul Hartig and colleagues review the recent deliberations of the Serotonin Club Nomenclature Committee∗ and outline a number of its recommendations aimed at encouraging consistency in current and future receptor nomenclature. Based on these principles, the present classification of 5-HT 1B and 5-HT 1D receptors is reconsidered, and a revised nomenclature for 5-HT 1B, 5-HT 1Dα and 5-HT, 1Dβ receptor subtypes is suggested.
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