Abstract
The association between “Alice in Wonderland” Syndrome (AWS) and infectious mononucleosis (IM) has been previously described in three patients. We describe two additional cases in children, where in one case, the visual symptoms of AWS appeared during the course of active IM and in the second, 2 weeks following a clinically mild, but serologically proven attack.
Highlights
Visual illusions characterized by distortion ofform, size, reciprocal position of objects, movement or colour, was initially labelled as "Alice in Wonderland" syndrome (AWS) by Lippman (1952)
We describe two additional cases with AWS associated with 1M in whom the visual symptoms appeared during the active course of the illness and 2 weeks following 1M respectively
Various neurological and psychiatric symptoms and signs have been described in association with infectious mononucleosis (Copperman, 1977; Hendler et at., 1978; Fisher et at., 1980)
Summary
Visual illusions (metamorphopsia) characterized by distortion ofform, size, reciprocal position of objects, movement or colour, was initially labelled as "Alice in Wonderland" syndrome (AWS) by Lippman (1952). The syndrome has been described in various neurological and psychiatric conditions including epilepsy, following the ingestion of hallucinogenic drugs (lysergic acid, diethylamide or marijuana), acute febrile states, schizophrenia and migraine (Adams and Victor, 1985; Golden, 1979). The association between AWS and infectious mononucleosis (1M) was originally described by Copperman (1977) reporting three children with visual illusions as the initial symptoms of 1M. We describe two additional cases with AWS associated with 1M in whom the visual symptoms appeared during the active course of the illness and 2 weeks following 1M respectively
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