Abstract
Two lines of mice that differ in their sensitivity to acute hypnotic effects of ethanol were tested for alcohol withdrawal reactions after a standard 3-day exposure to ethanol. The “long-sleep” strain showed a much milder withdrawal reaction than did the “short-sleep” strain. The two strains did not differ in sensitivity to convulsions elicited by pentylenetetrazol. Sleep times and withdrawal reactions did not correlate in individual mice of the genetically heterogeneous stock from which the two lines were derived.
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