Abstract

A crucial point in the recovery of substance use disorders (SUDs) is related to the difficulty for clinicians to detect and quantify the impact of psychiatric comorbidity on individual patients. The frequent co-occurrence of SUD with other psychiatric syndromes (e.g. mood, anxiety, thought disorder) raises important questions about the potential mechanisms, which are likely to vary depending on the associated disease, and the way to treat it. Based on the transdiagnostic framework, the present chapter examines the comorbidity between alcohol use disorder (AUD) and internalising disorders (e.g. depression), externalising disorders (e.g. other SUDs) and thought disorders (e.g. psychosis). Potential biopsychosocial mechanisms involved in the co-occurrence of symptoms, syndromes or dimensional traits were also considered. We discussed the fact that this dimensional approach in psychopathology offers a new horizon for research that can considerably improve the treatment of AUD in association with non-AUD symptoms and syndromes.

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