Abstract
The aim of this original research is to evaluate the effect of SG on alcohol intake symptoms, blood alcohol content (BAC), and alcohol metabolite levels. At 0-6-12months after SG, BAC of patients was measured at 0, 15, 30, and 60min, and then every 30min, and urinary metabolite (ethanol and acetaldehyde) levels were measured 2h after consuming a standard red wine drink. Symptoms perceived by patients were evaluated using symptom alcoholization post-obesity surgery scores. Thirty obese patients (12 men/18 women; mean body mass index, 44 ± 4kg/m2) who underwent SG were enrolled in this study. At 12months after SG, no alcohol use disorder was observed and BAC tended to peak after 15min, with alcohol intoxication symptoms (nausea/vomiting, flushing, and diaphoresis), and return to zero after 90min of wine intake. Ethanol and acetaldehyde levels were significantly different at 12months compared with the levels at time 0 (p < 0.05). Following SG, patients exhibit a high BAC at 15min after moderate alcohol consumption accompanied with increased metabolite excretion and intoxication symptoms. Level III obtained from well-designed cohort analytic study.
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