Abstract
Background and Aim: Alcohol is one of the major causes of liver cirrhosis worldwide. Patients with alcohol-related liver diseases are highly predisposed to infection. It is reported that, neutrophils counts are higher in peripheral blood and liver tissue of these patients. Neutrophils are the first responders to infection and tissue injury and optimal neutrophil function is important in disease resolution. Thus, our objectives were to investigate the effects of alcohol on neutrophil function, gene expression and ability to resolve infection.
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