Alcohol Ethoxylates Enhancing the Cuticular Uptake of Lipophilic Epoxiconazole Do Not Increase the Rates of Cuticular Transpiration of Leaf and Fruit Cuticles.

Abstract

Surfactants are known to enhance the foliar uptake of agrochemicals by plasticizing the transport-limiting barrier of plant cuticles. The effects of two different polydisperse alcohol ethoxylates with a low degree [mean ethoxylation of 5 ethylene oxide units (EOs)] and a high degree (mean ethoxylation of 10 EOs) of ethoxylation on cuticular barrier properties were investigated. The diffusion of the lipophilic organic molecule 14C-epoxiconazole and of polar 3H-water across cuticles isolated from six different plant species was investigated. At low surfactant coverages (10 μg cm-2), the diffusion of water across the cuticles was not affected by the two surfactants. Only at very high surfactant coverages (100-1000 μg cm-2) was the diffusion of water enhanced by the two surfactants between 5- and 50-fold. Unlike that of water, the diffusion of epoxiconazole was significantly enhanced 12-fold at surfactant coverages of 10 and 100 μg cm2 by the surfactant with low ethoxylation (5 EOs), and it decreased to 6-fold at a surfactant coverage of 1000 μg cm-2. The alcohol ethoxylate with a high degree of ethoxylation (10 EOs) only weakly increased the epoxiconazole diffusion. Our results clearly indicate that those surfactants that significantly enhance the uptake of the lipophilic agrochemicals (e.g., epoxiconazole) at a realistic leaf surface coverage of 10 μg cm-2, as is applied in the field, do not interfere with cuticular transpiration as an unwanted negative side effect.