Abstract
Epidemiological studies from many parts of the world have reported alcohol consumption as a risk factor for oesophageal squamous cell carcinoma (ESCC) and that this relationship is dose-dependent,1 but evidence from Africa has been inconsistent.2 In sub-Saharan Africa, the burden of ESCC is substantially higher in the eastern regions than western regions,3 but reasons for this difference are yet to be established. There is evidence that the total adult consumption of alcohol per capita is higher in western Africa than eastern Africa, suggesting that alcohol consumption on its own is unlikely to be driving these observed differences in disease burden.
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