Abstract
New information from neuroimaging studies on alcohol use disorders (AUDs) is available which necessitates an update on our review on alcohol and the human brain published in 2010. Here, we provide an overview on functional Magnetic Resonance Imaging (fMRI) and imaging genetics studies published in the last 5 years. Our systematic search in PubMed yielded a total of 70 fMRI studies out of which 57 were finally considered. We have summarized the study results based on their main research focus as follows: studies on neural correlates of reward processing (alcohol cues (N = 17), non-drug cues (N = 3)), decision making (N = 2), attention (N = 5), impulsivity and cognitive control (N = 1), pharmacological effects/treatment responses (N = 13) and relapse prediction (N = 6). Neuroimaging genetics studies have mainly considered the impact of various functional polymorphisms on alcohol cue processing (N = 10). These results indicate that recent research on AUDs has concentrated on reward processing (mainly alcohol cue reactivity). Possible directions for future research are discussed.
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