Abstract
The effect of ethanol on the absorption of L-methionine was studied in the human small intestine. It was shown that 2% ethanol significantly (P < 0.01) inhibited the absorption of this amino acid by 55%. A 40-g dose of alcohol was given orally to human volunteers as 10 and 20% solutions. Ethanol in the intestinal fluid reached concentrations of 2.5 to 3% and was maintained above 1% for 30 to 60 minutes. The possible significance of these findings is discussed in relation to the nutritional deficiencies that occur in chronic alcoholism in humans.
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