Abstract
SESSION TITLE: Severe Sepsis & Septic Shock SESSION TYPE: Original Investigation Poster PRESENTED ON: Wednesday, November 1, 2017 at 01:30 PM - 02:30 PM PURPOSE: Hospitalized patients with hypoalbuminemia are known to have increased mortality. We aimed at assessing the predictive power of hypoalbuminemia on mortality and length of hospital stay in patients with sepsis. METHODS: A retrospective study (June 2014 to June 2016) was conducted comparing all patients with suspected infection admitted to Northside medical center ER, patient information include age, basic metabolic index, serum albumin level, mortality and length of hospital stay. A linear regression module was used to assess the association between serum albumin level, length of hospital and mortality. RESULTS: We included 723 patients and albumin was available in 706 (92.5%). A total of 43 (5.6%) patients died while in the hospital. Median plasma albumin was 30 g/L (IQR 25-34). Patients with low albumin had higher mortality and were admitted for a longer period than patients with a normal albumin, while patients with high albumin had a lower mortality, and were admitted for a shorter period. Linear regression analyses confirmed the association of hypoalbuminemia with mortality (unstandardized coefficients: -0.63 (95% CI: -0.91--0.035. P value <0.001)) and length of hospital stay (unstandardized coefficients: -0.399 (95% CI: -0.427--0.251. P value <0.001)). CONCLUSIONS: We found hypoalbuminemia to be associated with increase mortality and length of hospital stay in patient with sepsis. CLINICAL IMPLICATIONS: Used as predictive tool for mortality, plasma albumin had acceptable discriminatory power and further long term larger studies are needed to evaluate if improving patients nutrition status early through feeding or even intravenous albumin will improve overall mortality and decrease total hospital stay DISCLOSURE: The following authors have nothing to disclose: Tamer Said Ahmed, Tabassum Nafsi, Praful Tewari, Nikhil Kalra, Shahi Diwas Diwas, Ajai Rajabalan, Mehreen Elahee, Arslan Talat No Product/Research Disclosure Information
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