Alarming high prevalence of metabolic syndrome among Jordanian adults.

Ahmad Abdallah Obeidat,Fares Halem Haddad,Mousa Numan Ahmad,Firas Sultan Azzeh

doi:10.12669/pjms.316.7714

Ahmad Abdallah Obeidat, Fares Halem Haddad + Show 2 more

Open Access

https://doi.org/10.12669/pjms.316.7714

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Abstract

Objective:To evaluate the prevalence and the individual components of metabolic syndrome (MetS) in Jordanian adults.Methods:In this cross sectional study, 630 adult subjects (308 men and 322 women) aged between 20-70 years were recruited from the clinics at the King Hussein Medical Center. The diagnosis of MetS was made according to the International Diabetes Federation (IDF) criteria-2005. Blood samples were collected after 10-12 hours overnight fasting and serum was obtained for biochemical analysis.Results:The prevalence of metabolic syndrome according to IDF criteria was 51% (46.4% in men and 55.3% in women). Prevalence of increased waist circumference in the total sample was 71.6%, 46% for high blood pressure, 42.4% for elevated fasting blood glucose, 43.5% for low high density lipoprotein, and 50.2% for hypertriglyceridemia.Conclusion:The prevalence and individual components of MetS in Jordan were high. Screening of MetS is needed at national level to reduce the incidence of Type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD).

Highlights

Metabolic syndrome (MetS) is a huddle of interrelated metabolic risk factors that increase the risk of cardiovascular morbidity and mortality.[1,2,3] The frequently documented factors include insulin resistance or glucose intolerance, central/ abdominal obesity, hypertension and dyslipidemia, decreased high density lipoprotein cholesterol (HDL-C) and hypertriglyceridemia (high blood triglycerides (TG))
Prevalence of increased WC in the total sample was 71.6%, while 46%, 42.4%, 43.5%, and 50.2% of the total sample were high in BP, elevated FBG, low in HDL, and having hypertriglyceridemia, respectively
Males were found to be higher in elevated FBG and hypertriglyceridemia than females, whereas other components were lower

Summary

Introduction

Metabolic syndrome (MetS) is a huddle of interrelated metabolic risk factors that increase the risk of cardiovascular morbidity and mortality.[1,2,3] The frequently documented factors include insulin resistance or glucose intolerance, central/ abdominal obesity, hypertension and dyslipidemia, decreased high density lipoprotein cholesterol (HDL-C) and hypertriglyceridemia (high blood triglycerides (TG)). These factors are the major risk factors for cardiovascular disease (CVD).[1,3] MetS is essentially considered as a product of interaction between multiple genetic and environmental factors, though its pathogenesis is not clearly determined.[4]. The syndrome is widely accepted as an important risk factor for CVD, in addition to other environmental/

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