Abstract
The PERSIAN Kavar cohort study (PKCS) aims to investigate the prevalence, trends, and relevant prognostic risk factors of non-communicable diseases in participants aged 35–70 years living in the urban area of Kavar County. Kavar County is located at the center of Fars province in the southwest of Iran. Overall, 5236 adults aged 35–70 years old were invited to participate in the PKCS. From whom, 4997 people comprising 2419 men and 2578 women met the inclusion criteria and were recruited in the study (participation rate: 95.4%). This study is aimed to follow participants for at least 10 years; it is designed to perform all procedures similar to the primary phase including biological sampling, laboratory tests, physical examinations, and collecting general, nutritional, and medical data at the 5th and 10th years of follow-up. In addition, participants are annually followed-up by phone to acquire data on the history of hospitalization, any major diagnosis or death. At the enrollment phase, trained interviewers were responsible for obtaining general, nutritional, and medical data utilizing a 482-item questionnaire. The results of the baseline phase of this study show that the overweight category was the most prevalent BMI category among the registered participants (n = 2005, 40.14%). Also, almost one-third of Kavar adult population suffered from metabolic syndrome at the baseline phase (n = 1664, 33.30%). The rate of eighteen-month follow-up response was 100% in the PKCS. Hypertension (n = 116, 2.32%), cardiovascular outcomes (n = 33, 0.66%), and diabetes (n = 32, 0.64%) were the most prevalent new-onset NCDs during eighteen months of follow-up in the participants.
Highlights
A few decades ago, communicable diseases were the leading cause of death in developing countries [1]
The Fars and Turk nomad ethnicities were the dominant ethnicities in Kavar urban district (96.28%)
The participation rate in this study was 95.4%, which was higher than the reported rates in other PERSIAN cohorts, such as the Ravansar Non-Communicable Disease (RaNCD) (93.2%) [27], the Guilan Cohort (PGCS) (83.2%) [28], the Hoveyzeh Cohort (HCS) (82.7%) [29], the Rafsanjan Cohort (RCS) (67.42%) [30], and the Tabari Cohort studies (TCS) (61.7%) [31]
Summary
A few decades ago, communicable diseases were the leading cause of death in developing countries [1]. The mortality associated with communicable, maternal, neonatal, and nutritional disorders reduced from the annual rate of 16.1 million deaths in 1990 to 11.8 million deaths in 2013 [2, 3]. Transition to modern lifestyle and higher life expectancy can increase NCDs risk factors and subsequently cause an outbreak in NCDs incidence rate [5]. Developments in the health care system, namely the advancements in controlling infectious diseases, have extended life expectancy in the Iranian population [7]. The modernization of Iranian’s lifestyle, the acquisition of western dietary patterns and low physical activity, accompanied by the extended life span put a higher percentage of Iranians at risk for NCDs [7,8,9]
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
