Abstract
Aim. To discuses challenges with diagnosis of primary AL-amyloidosis as exemplified by a case study; to analyse the key steps of diagnostic search of systemic amyloidosis in a female patient with a comorbidity. Key points. In an elderly woman complaining of generalised oedema, shortness of breath, arterial hypertension, at an early stage of diagnostic search, assumptions were made that her oedema was caused by cardiac disorders and that she had congestive heart failure. Given urinary syndrome, azotemia, hypoproteinaemia diagnosed during an initial examination in a district hospital, the patient was referred to the Nephrology Department of the Republican Clinical Hospital of the Ministry of Health of the Republic of Tatarstan, where a comprehensive staged follow-up examination confirmed AL-amyloidosis with kidney, liver, heart involvement. Conclusion. We have demonstrated challenges with timely diagnosis of systemic amyloidosis as exemplified by a case study in an elderly patient with a comorbidity. Keywords: AL-amyloidosis, elderly age, nephrotic syndrome.
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