Abstract
α - terpineol is a compound of the class of terpenoid alcohols derived from natural materials , α - terpineol can be synthesized from α - pinene from turpentin content of extracts derived from the sap of pine trees ( Pinus merkusii ). α - terpineol has been reported as a natural compound that has potential as anticancer agent. Objectives of research : In general, to assess the activity of α - terpineol compounds against HeLa cells and the possible mechanism, whereas specifically assessing cytotoxic activity. Methods : This was a quasi-experimental study using post-test only with non-equivalent control group design. This study was conducted on HeLa cells by administering α-terpineol. Observations cytotoxic activity assay was performed using MTT assay method. Results : α -terpineol was cytotoxic against HeLa cells with IC 50 of 12,46 μg/mL , therefore this compound was a potential anticancer Kata kunci : α-terpineol, sitotoksik, HeLa, kanker leher rahim
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