Aktivitas Antioksidan Ekstrak Etanol Herba Pegagan (Centella asiatica (L.) Urban) Dengan Metode DPPH (2,2-Difenil-1-Pikrilhidrazil)

Abstract

Unhealthy lifestyles and air pollution cause the number of free radicals in the body to increase. To protect the body from free radicals, there are antioxidant compounds as an antidote and stabilize free radicals. One of the Indonesian plants that can be used as antioxidants is gotu kola (Centella asiatica (L.) Urban. This study aims to determine the antioxidant activity from hand and body lotion extract of gotu kola by DPPH (2,2-Diphenyl-1-Picrylhydrazyl) method which is expressed as an IC50 value. Gotu Kola (Centella asiatica (L.) Urban) was extracted by the soxhletation method using a solvent etanol 96% and formulated in the from of hand and body lotion using variations of gotu kola extract concentrations of 1%, 3% and 5%. Then do a physical evaluation of three preparations of hand and body lotion to determine the best formula to be tested for antioxidant activity. Hand and body lotion preparation formula with as much gotu kola extract concentration 5% shows the best formula. The results of testing antioxidant activity on hand and body lotion showed IC50 value of 449.14 ppm. This indicates that the Antioxidant activity of gotu kola extract hand and body lotion is included in the very weak antioxidant criteria.