Abstract
Optical coherence tomography (OCT) is a noninvasive imaging modality that can provide high-resolution, cross-sectional images of tissues. Especially in retinal imaging, OCT has become one of the most valuable imaging tools for diagnosing eye diseases. Considering the scattering and absorption properties of the eye, the 1000-nm OCT system is preferred for retinal imaging. In this study, we describe the use of an akinetic swept-source OCT system based on a pulse-modulated active mode locking (AML) fiber laser at a 1080-nm wavelength for in-vivo human retinal imaging. The akinetic AML wavelength-swept fiber laser was constructed with polarization-maintaining fiber that has an average linewidth of 0.625 nm, a spectral bandwidth of 81.15 nm, and duty ratio of 90% without the buffering method. We successfully obtained in-vivo human retinal images using the proposed OCT system without the additional k-clock and the frequency shifter that provides a wide field of view of 43.1°. The main retina layers, such as the retinal pigment epithelium, can be distinguished from the OCT image with an axial resolution of 6.3 μm with this OCT system.
Highlights
Optical coherence tomography (OCT) is a noninvasive imaging modality that can provide high-resolution, cross-sectional images of tissues[1,2,3]
We describe the use of a pulse-modulated active mode locking (AML) wavelength-swept fiber laser with a 1080-nm wavelength for in-vivo human retinal OCT imaging
The laser cavity consisted of an semiconductor optical amplifier (SOA), optical circulator, and chirped fiber Bragg grating (CFBG) and electro-optic intensity modulators
Summary
Optical coherence tomography (OCT) is a noninvasive imaging modality that can provide high-resolution, cross-sectional images of tissues[1,2,3]. An InGaAs CCD camera can be used for a 1000-nm SD-OCT system; it is not cost effective, and it has a low pixel number, making it difficult to obtain an OCT image of the deeper retinal layer Another high-speed OCT system is swept-source OCT (SS-OCT), which uses a wavelength-swept laser as the light source. The sweeping behaviors are determined by the mechanical movements of the wavelength-tunable components, such as a the Fabry-Perot tunable filter[18,19], a polygon mirror scanner[20], tunable microelectromechanical system filter with a semiconductor optical amplifier (SOA)[21], or vertical cavity surface-emitting laser[7,16]. Unstable or drifting mechanical movements can lead to overall degradation of source performance[11,14,15,22]
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