Airway exposure to diesel exhaust particles and urban particulate matter induces allergic sensitization to peanut via distinct mechanisms

Abstract

Exposure to traffic-related air pollutants is associated with sensitization to foods through unknown mechanisms. We previously reported that airway co-exposure to peanut and either diesel exhaust particles (DEP) or urban particulate matter (UPM) induces peanut allergy in an animal model. Here, we investigated the immune mechanisms by which these pollutants induce airway sensitization.