Abstract
AIDS-Related Pathology
Highlights
A variety of diseases may be encountered related directly and/or indirectly to human immunodeficiency virus (HIV) infection
This is demonstrated in the beautifully illustrated article about multiple pathologies seen in skin biopsies from patients with HIV/acquired immune deficiency syndrome (AIDS), as well as the comprehensive review of HIV-related cytopathology
The case report describing HHV-8 infection associated with Kaposi sarcoma (KS), multicentric Castelman s disease (MCD), and plasmablastic microlymphoma in a single lymph node of a Kenyan man with AIDS commendably reviews the pathology of this oncogenic process
Summary
A variety of diseases may be encountered related directly and/or indirectly to HIV infection. Rare manifestations of common diseases and common presentations of rare conditions may be seen together; only HIV and its subsequent immunosuppression link these phenomena. With the advent of HAART in established market economies, the spectrum has changed with a notable shift from infection to cancer and “standard” diseases that non-HIV-infected people are routinely affected by, but often their manifestations have subtle differences.
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