Abstract

Cryptosporidium localization to the stomach is uncommon. We report a case of a 56-year-old, HIV-positive, male patient with severe immunosuppression after antiretroviral treatment dropout who presented with epigastric discomfort, nausea and vomiting. The abdominal CT with contrast showed an important concentric thickening of the gastric antrum wall. Upper gastrointestinal endoscopic evaluation revealed lack of distensibility of the gastric wall and marked thickening, stiffness, distortion, and erosions of mucosal folds involving the antrum region. The endoscopy was clinically reported as gastric malignancy suggestive of lymphoma. The histopathologic diagnosis was cryptosporidiosis. To our knowledge, gastric cryptosporidiosis simulating malignancy has not been previously described. This type of lesion should be included in the differential diagnosis of AIDS patients with lesions simulating gastric malignancy. La localización del Cryptosporidium en el estómago es infrecuente. Se presenta el caso de un paciente de 56 años de edad, VIH-positivo, con inmunosupresión severa, después de abandonar el tratamiento anti-retroviral, que presentó malestar epigástrico, náuseas y vómitos. La TC abdominal con contraste mostró un engrosamiento concéntrico importante del antro gástrico. La evaluación endoscópica gastrointestinal reveló falta de distensibilidad de la pared gástrica y marcado engrosamiento, junto con rigidez, distorsión y erosión de los pliegues de la mucosa del antro. El estudio endoscópico fue informado como proceso maligno sugestivo de linfoma. El diagnóstico histopatológico fue de criptosporidiosis. De acuerdo con nuestro conocimiento, la criptosporidiosis gástrica simulando un tumor maligno no ha sido descrita. Este tipo de lesión se debe incluir en el diagnóstico diferencial de pacientes VIH+ con lesiones que sugieran malignidad gástrica.

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