Abstract

This paper reviews state-of-the-art research solutions across the spectrum of medical imaging informatics, discusses clinical translation, and provides future directions for advancing clinical practice. More specifically, it summarizes advances in medical imaging acquisition technologies for different modalities, highlighting the necessity for efficient medical data management strategies in the context of AI in big healthcare data analytics. It then provides a synopsis of contemporary and emerging algorithmic methods for disease classification and organ/ tissue segmentation, focusing on AI and deep learning architectures that have already become the de facto approach. The clinical benefits of in-silico modelling advances linked with evolving 3D reconstruction and visualization applications are further documented. Concluding, integrative analytics approaches driven by associate research branches highlighted in this study promise to revolutionize imaging informatics as known today across the healthcare continuum for both radiology and digital pathology applications. The latter, is projected to enable informed, more accurate diagnosis, timely prognosis, and effective treatment planning, underpinning precision medicine.

Highlights

  • M EDICAL imaging informatics covers the application of information and communication technologies (ICT) to medical imaging for the provision of healthcare services

  • It was defined by the Society for Imaging Informatics in Medicine (SIIM) as follows [1]–[3]: “Imaging informatics touches every aspect of the imaging chain from image creation and acquisition, to image distribution and management, to image storage and retrieval, to image processing, analysis and understanding, to image visualization and data navigation; to image interpretation, reporting, and communications

  • Biomedical imaging has revolutionized the practice of medicine with unprecedented ability to diagnose disease through imaging the human body and high-resolution viewing of cells and pathological specimens

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Summary

INTRODUCTION

M EDICAL imaging informatics covers the application of information and communication technologies (ICT) to medical imaging for the provision of healthcare services. A wide-spectrum of multi-disciplinary medical imaging services have evolved over the past 30 years ranging from routine clinical practice to advanced human physiology and pathophysiology. It was defined by the Society for Imaging Informatics in Medicine (SIIM) as follows [1]–[3]:. Digital pathology visualization challenges are further documented while in-silico modelling advances are presented debating the need of introducing new integrative, multi-compartment modelling approaches.

IMAGE FORMATION AND ACQUISITION
Feature Analysis
Machine Learning
Deep Learning for Segmentation
Deep Learning for Classification
CNN Interpretability
Interpretation and Understanding
Segmentation and Classification
Biomedical 3D Reconstruction and Visualization
In Silico Modeling of Malignant Tumors
Digital Twins
Medical Imaging in the Era of Precision Medicine
Radiogenomics for Integrative Analytics
Integrative Analytics in Digital Pathology
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