Abstract
Introduction: Aging may impair healing and promote adverse remodeling after reperfused myocardial infarction (RMI) whereas healing-specific proteins such as secretory leucocyte protease inhibitor (SLPI), secreted protein acidic and rich in cysteine (SPARC) and osteopontin (OPN) may improve healing and remodeling after RMI. Matrix metalloproteinase (MMP)–9 and tissue inhibitor of MMP (TIMP)–3 imbalance contributes to remodeling and dysfunction after RMI. We sought to determine whether aging upregulates SLPI, SPARC, OPN, MMP–9 and cytokines tumor necrosis factor (TNF)-α and transforming growth factor (TGF)-β1 in acute RMI.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
