Abstract
Female fertility begins to decline many years prior to the onset of menopause despite continued regular ovulatory cycles. Although there is no strict definition of advanced reproductive age in women, infertility becomes more pronounced after the age of 35. A classic report on the effect of female age on fertility found that the percentage of women not using contraception who remained childless rose steadily according to their age at marriage: 6% at age 20 to 24, 9% at age 25 to 29, 15% at age 30 to 34, 30% at age 35 to 39, and 64% at age 40 to 44 (1).
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