Abstract
The giant cell central lesion (LCCG) is considered to be rare and benign, and its etiology is uncertain. Clinically and radiographically, it can be differentiated between aggressive and nonaggressive lesions. A female patient with leukoderma, 13 years old, presented with discrete asymmetry in the right hemiface and increased volume in the anterior region of the mandible, of indurated consistency, and painless palpation. In the imaging examinations, the presence of a radiolucent, multilocular, well-delimited image in the anterior region of the mandible crossing the midline, with tooth dislocation was observed. Histopathology revealed a loose, richly vascularized fibrous connective tissue fragment exhibiting intense proliferation of spindle and oval cells with large numbers of nonspecific multinucleated giant cells. Hemorrhagic areas and deposits of brownish pigmentation were compatible with hemosiderin. The diagnosis was central giant cell lesion. The conservative drug therapy was performed, which was not successful, and the surgical intervention was performed. Postoperative control is 6 months, without recurrence.
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