Abstract

Borderline tumors are non-invasive neoplasms that have nuclear abnormalities and mitotic activity intermediate between benign and malignant tumors of similar cell types. Its diagnosis poses a problem because of its malignant tendencies and non-specific routine light microscopic features. The present case aims to report a malignant mesenchymal neoplasm with suggestive histopathologic diagnosis of fibrosarcoma of mandible in a 13-year-old female patient. Microscopically, the tumor showed proliferation of spindle-shaped cells, varying little in size and shape, and arranged in parallel bands, partly crossing each other. Immunohistochemical profile was AML positive and S100 - HHF35 negative. Based on clinical, radiologic and histologic findings the diagnosis was suggestive of intraosseous fibrosarcoma and the patient was referred for treatment in a reference center. Patient refused surgical resection of mandible as first choice treatment, opting for chemotherapy and radiotherapy to restaging the tumor. The patient currently is under treatment.

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