Aggressive Angiomyxoma of Vulva

Madhav Panthi,Neeta Kafle,Tarun Pradhan

doi:10.3126/bjhs.v6i3.43246

Abstract

Aggressive angiomyxoma is a rare, slowly growing, and benign tumor of mesenchymal origin that usually occurs in the pelvis and perineum of young females. Steeper and Rosai in 1983, first described angiomyxoma. The term “aggressive” underlines the tumour’s locally infiltrative nature and high risk for local recurrence. The rate of relapse varies from 35% to 72%, however, it rarely metastasizes so it has an overall good prognosis. Diagnosis is mainly made on histopathology after surgical resection. The optimal treatment for aggressive angiomyxoma is wide local excision with tumor free margin. We here report a case of aggressive angiomyxoma in 22 years female who presented with mass on left labia majora.

Highlights

Angiomyxoma is so ssue neoplasm with a predilec on for pelvic and perineal regions and has a tendency for local recurrence
Female to male ra o is 6.6/1 and the term “aggressive” underlines the tumour's locally infiltra ve nature, but mostly the high rate of local recurrence.3It usually presents as a vulval polyp and is diagnosed on histopathology
Aggressive angiomyxomasmainly occurs on the vagina, vulva pelvic cavity, perineum, hips and crissum in reproduc ve female

Summary

INTRODUCTION

Angiomyxoma is so ssue neoplasm with a predilec on for pelvic and perineal regions and has a tendency for local recurrence. It is composed of small stellate and spindle cells in a myxoedematousstroma with entrapped regional structures.[1]. Steeper and Rosai in 1983, first described angiomyxoma and reported a case series of 9 female pa ents.[2]. We here report first diagnosed case of aggressive angiomyxoma in our ins tu on in 22 year old female. Examina on of perineum revealed a pedunculated mass from le labia majora measuring approximately 10cm x 8cm x 4cm with stalk 4cm (Figure[1]).

DISCUSSION

CONCLUSION