Abstract
The epidemiological significance of agglutinins against Group III atypical mycobacteria was studied by testing a panel of sera with nine different M. intracellulare antigens. Five of them represented “common” types most frequently isolated from clinical specimens; the other four represented “rare” types never isolated from such specimens. Agglutinins were detected in human sera more frequently against the “common” types than against the “rare” types. The greatest proportion of reactive sera and the highest titres were found with the serotype Chance antigen. In bovine and porcine sera there was no difference in the occurrence of antibodies against the “common” and “rare” serotypes, and the serotype Chance antigen did not exhibit any exceptional reactivity. The observations are compatible with the view that the antibodies in human sera to a considerable extent result from immunization by the mycobacterium type used for serological testing or a closely related type.
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Schedule a callMore From: Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology
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