Agglutination Effect of Selected Medicinal Plant Leaf Crude Extracts on A-B-O Blood Group

Abstract

This study was conducted to test the agglutinating properties of leaf crude extracts of selected plants on human A-B-O blood group. The experimental plants used were as follows: kasapi-sapi (<i>Ageratum conyzoides L.</i>), Vicks (<i>Origanum vulgare L.</i>), Sabi (<i>Chenopodium ambrosioides L.</i>), Dunggaw (<i>Bryophylum pinnata L.</i>). The blood types of the 90 blood donors were pre-determined using the commercially available anti-sera A and B. Each blood samples were tested with the four plant leaf crude extracts for the agglutination reaction and were examined under the microscope. Presence of agglutination of red blood cells was marked as positive and absence of such reaction was marked as negative. The result had shown that kasapi-sapi (<i>A. conyzoides L.</i>) and Sabi (<i>C. ambrosioides L.</i>) did not cause agglutination of red blood cells in any of the human blood types. Dunggaw (<i>B. pinnata L.</i>) and Vicks (<i>O. vulgare L.</i>) leaf crude extracts did cause agglutination of the red blood cells from the donors, but, not to a specific blood type. Thus, none of the experimental plants could serve as a substitute for commercially produced anti-sera but could serve as first aid during emergency cases to stop excessive bleeding.