Abstract
This study was conducted to test the agglutinating properties of leaf crude extracts of selected plants on human A-B-O blood group. The experimental plants used were as follows: kasapi-sapi (<i>Ageratum conyzoides L.</i>), Vicks (<i>Origanum vulgare L.</i>), Sabi (<i>Chenopodium ambrosioides L.</i>), Dunggaw (<i>Bryophylum pinnata L.</i>). The blood types of the 90 blood donors were pre-determined using the commercially available anti-sera A and B. Each blood samples were tested with the four plant leaf crude extracts for the agglutination reaction and were examined under the microscope. Presence of agglutination of red blood cells was marked as positive and absence of such reaction was marked as negative. The result had shown that kasapi-sapi (<i>A. conyzoides L.</i>) and Sabi (<i>C. ambrosioides L.</i>) did not cause agglutination of red blood cells in any of the human blood types. Dunggaw (<i>B. pinnata L.</i>) and Vicks (<i>O. vulgare L.</i>) leaf crude extracts did cause agglutination of the red blood cells from the donors, but, not to a specific blood type. Thus, none of the experimental plants could serve as a substitute for commercially produced anti-sera but could serve as first aid during emergency cases to stop excessive bleeding.
Highlights
Blood as a connective tissue, has multiple functions
Kasapi-sapi (A. conyzoides) leaf crude extract did not cause agglutination of red blood cells in all blood samples. Such result implied that A. conyzoides leaf crude extract may not contain agglutinins that could bind to antigen A and /or B on the human red blood cells resulting to the absence of agglutination of the blood samples of the A-BO group
The result of this study showed that the agglutination reaction test of the different blood types mixed with the plant leaf crude extracts namely: dunggaw (B. pinnata), and vicks (O. vulgare), caused agglutination reaction in all of the A-B-O blood groups
Summary
Blood as a connective tissue, has multiple functions. It transport oxygen, nutrients, and other solutes to cells. It carries away their secretions including hormones and metabolic wastes. It serves as a highway for phagocytic cells that scavenge tissue debris and fight infection. It does this by carrying excess heat from skeletal muscles and other regions of high metabolic activity to the skin, where heat can be dissipated [4]
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