Abstract
Address: 1Department of Trauma and Orthopaedics, Tzanio General Hospital NHS, Tzani and Afendouli, 18536, Piraeus, Greece, 2Department of Trauma and Orthopaedics, Thriasio General Hospital NHS, G, Gennimata Av, 19600, Magoula, Attica, Greece and 3The Centre for Spinal Studies & Surgery, Nottingham University Hospitals Trust, Queen's Medical Centre Campus, Nottingham NG7 2UH, UK, D. Bernardou 31 Brilissia, Attica, 15235, Greece
Highlights
6th International Conference on Conservative Management of Spinal Deformities Jean Claude de Mauroy, Theodoros Grivas, Patrick Knott and David Tager A single PDF containing all abstracts in this Supplement is available here.
The development of menarche could be explored for evidence of hormesis
Hormesis is defined as the response of cells or organisms to an exogenous substance or an intrinsic factor in which the factor induces stimulatory or beneficial effects at low doses and inhibitory or adverse effects at high doses [bimodal dose-response] or vice versa
Summary
Age variations of melatonin level and its hormesis; implications for AIS and osteoporosis. Address: 1Department of Trauma and Orthopaedics, "Tzanio" General Hospital - NHS, Tzani and Afendouli, 18536, Piraeus, Greece, 2Department of Trauma and Orthopaedics, "Thriasio" General Hospital - NHS, G, Gennimata Av, 19600, Magoula, Attica, Greece and 3The Centre for Spinal Studies & Surgery, Nottingham University Hospitals Trust, Queen's Medical Centre Campus, Nottingham NG7 2UH, UK, D. The "light of night", is a very important hormone for the function of the human organism. The levels continue to decline gradually during middle age. In an older population the levels of melatonin in the serum are very low. Melatonin is involved in human sexual maturation and declines, affecting menses and osteogenesis
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