Abstract
The binding of labeled agonist (3H-prazosin) to α1-receptors in the frontal cortex, hypothalamus, and medulla oblongata of hypertensive (NISAG) and normotensive (Wistar) rats of different age is studied to elucidate the role of these receptors in the development of hereditary stress-induced arterial hypertension. It is found that the density of α1-adrenoceptors in the hypothalamus of 30-day-old and adult NISAG rats is decreased, while in the medulla oblongata the number of these receptors, starting from the first week of life, is greater than in Wistar rats of the same age. From a comparison of these findings with the development of hypertension in NISAG rats it is concluded that α1-adrenoceptors of the medulla oblongata are involved in this process.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
