Abstract
Purpose: The main objective was to analyze the relationship between maximum cup depth (MCD), mean defect (MD), central corneal thickness (CCT), age and disc area, in patients with ocular hypertension (OHT) and primary open angle glaucoma (POAG). Methods: Cross-sectional study of patients diagnosed with OHT and POAG. Visual fields were obtained using an Octopus 300 analyzer, TOP strategy. MCD and disc area were obtained using a Heidelberg Retina Tomograph. Results: The study sample comprised 234 eyes of 143 patients, 91 women and 52 men, mean age 63.55 years (SD 10.49). Mean values were: MCD 0.52 mm (SD 0.27), MD 2.78 dB (SD 5.02), CCT 543.5 μm (SD 36.63), IOP 16.73 mmHg (SD 2.93), and disc area 2.01 mm2 (SD 0.39). A significant correlation was observed between MCD and age in patients under 60 years, between MCD and disc area, and between MD and disc area. Conclusions: Our study showed a correlation between MCD and age which was significant in patients under 60 years of age, between MCD and disc area and between MD and disc area, suggesting that the larger the disc area, the greater the MCD and the MD in patients with OHT and POAG.
Highlights
The main objective was to analyze the relationship between maximum cup depth (MCD), mean defect (MD), central corneal thickness (CCT), age and disc area, in patients with ocular hypertension (OHT) and primary open angle glaucoma (POAG)
As risk factors for progression, the Early Manifest Glaucoma Trial (EMGT) found that high intraocular pressure (IOP) contributed to POAG and pseudoexfoliation syndrome, more baseline damage, disc haemorrhages, thinner CCT, low blood pressure, and higher age [6]
Selection of the study sample: We selected a cross-sectional sample of patients diagnosed with OHT and POAG attending the Glaucoma unit at University Hospital of the Canary Island
Summary
The main objective was to analyze the relationship between maximum cup depth (MCD), mean defect (MD), central corneal thickness (CCT), age and disc area, in patients with ocular hypertension (OHT) and primary open angle glaucoma (POAG). Among other predisposing factors for glaucomatous damage, increased IOP produces direct compression of the axons of ganglion cells against the lamina cribrosa, interrupting blood flow and inducing cell death [3]. This association between loss of nerve fibers and IOP has been demonstrated and quantified withscanning laser polarimetry [4]. The main objective of the present work was to determine the maximum cup depth (MCD) in patients with OHT and POAG and study its relationship with mean defect (MD), age, CCT and disc area
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