Abstract
In present study echocardiographic features of the cardiovascular system in patients with nonalcoholic fatty liver disease (NAFLD) of different ages were examined. Structural and functional parameters of the heart change in nonalcoholic fatty liver patients with age: a progressive increase in the size of the left atrium, right ventricle, and decrease of ejection fraction. In young patients the formation of concentric remodeling and eccentric hypertrophy, in elderly patients – development of its concentric hypertrophy was observed. The above-mentioned requires timely use of cardio-protective drugs in the treatment of these patients.
Highlights
Various researchers pay attention to the role of nonalcoholic fatty liver disease (NAFLD) in the development and progression of alterations in the cardiovascular system
Indicators of central hemodynamics in NAFLD patients are characterized by increase of systolic and diastolic blood pressure, heart rate, total peripheral vascular resistance and cardiac output[4, 5]
All patients and healthy individuals were divided by age factor adopted by the European Regional Office of the WHO life periods classification (1963)
Summary
Various researchers pay attention to the role of NAFLD in the development and progression of alterations in the cardiovascular system. Numerous epidemiological studies suggest an increased incidence of adverse cardiovascular events in patients with NAFLD as compared with the general population [2, 8, 11]. E. Ruttmann et al studies for 12-year follow-up demonstrated a significant relationship between increased activity of gammaglutamyltransferase in NAFLD patients and cardiovascular mortality, even after adjustment of typical cardiovascular risk factors and normalization of body mass index [3]. S. Treeprasertsuketal showed that patients with NAFLD have a higher 10-year risk of coronary heart disease than an average person in general population of the same age and gender [10]. Indicators of central hemodynamics in NAFLD patients are characterized by increase of systolic and diastolic blood pressure, heart rate, total peripheral vascular resistance and cardiac output[4, 5]. The objective of our study was to examine echocardiographic features of the cardiovascular system in patients with NAFLD of different ages
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